Browsing Volume 1 Issue 3, 2010 by Issue Date
Now showing items 1-20 of 26
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Biochemical and pathological changes associated with avocado leaves poisoning in rabbits - A case report
(JK Welfare & Pharmascope Foundation, 2010-07-25)Avocado fruits are very popular among vegetarians as an excellent substitute for meats in sandwiches andsalads in some countries because of its high fat content. It is also one of the common fruits in the state of Mizoram, ... -
Investigation effect of pioglitazone, glimepiride, nobivolol, valsartan and hespe-ridine on glucose, HbA1c and blood pressure in experimentally induced myocardial infarction in type 2 diabetic rats
(JK Welfare & Pharmascope Foundation, 2010-07-25)Present study was designed to evaluate effect some synthetic drugs and some herbal compound on Glucose, HbA1c and Systolic and diastolic blood pressure in isoproterenol induced myocardial infarction in normal and ... -
Pharmacognostic and anti-hyperglycemic evaluation of Lantana camara(L.) var. aculeate leaves in alloxan-induced hyperglycemic rats
(JK Welfare & Pharmascope Foundation, 2010-07-25)Lantana camara (L.) var. aculeate (family: Verbenaceae) commonly called as wild sage is large scrambling evergreen, strong smelling shrub with stout recurred prickles; leaves opposite, often rugose, scabrid on both sides. ... -
Augmentation of endothelial dependent relaxation in thoracic aorta of streptozotocin induced diabetic rats: Role of Statins
(JK Welfare & Pharmascope Foundation, 2010-07-25)Oxidative stress is pathogenetic hypotheses of vascular complication in diabetes by impaired endothelial dysfunction (ED) and antioxidant status. The endothelium is complex organ essential for controlling vascular functions. ... -
Pharmacokinetics of amoxicillin loaded sepia Nanoparticles in healthy rabbits
(JK Welfare & Pharmascope Foundation, 2010-07-25)The main aim of the present study was to evaluate the Pharmacokinetic profiles amoxicillin nanoparticles after oral administrations in rabbits. The sepia nanoparticles were prepared by using the controlled gellification ... -
Development and validation of a RP-HPLC-PDA method for simultaneous esti-mation of Drotaverine and Aceclofenac in a combined dosage form
(JK Welfare & Pharmascope Foundation, 2010-07-25)A simple, precise, rapid and accurate RP-HPLC-PDA method has been developed for the simultaneous estimation of drotaverine HCl (DRT) and aceclofenac (ACE) in combined tablet dosage form. Formulation containing DRT with ACE ... -
Preparation and evaluation of Transdermal patches of Papaverine hydrochloride
(JK Welfare & Pharmascope Foundation, 2010-07-25)Transdermal patches of Papaverine hydrochloride were prepared by solvent casting method using ethyl cellulose: PVP, PVA: PVP and eudragit RL-100: eudragit RS-100 in different ratios. The physicochemical parameters like ... -
In vitro anthelmintic activity of Fenugreek seeds extract against Pheritima posthuma
(JK Welfare & Pharmascope Foundation, 2010-07-25)Crude extracts of Trigonella foenum-graecum (Leguminoceae) were evaluated for in-vitro anthelmintic activity on the Indian adult earthworms Pheritima posthuma. The seed extracts of Trigonella foenum-graecum had shown a ... -
Evaluation of Antioxidant and Hepatoprotective effects of 70 % ethanolic bark extract of Albizzia lebbeck in rats
(JK Welfare & Pharmascope Foundation, 2010-07-25)The Plant Albizzia lebbeck is reported to contain polyphenolic compounds. However, there are no reports on the antioxidant and organ protective properties of this plant. Hence, the present study was planned with an objective ... -
Synthesis and anti-convulsant screening of novel Schiff bases of 3-amino-2-methyl quinazolin-4-(3H)-one
(JK Welfare & Pharmascope Foundation, 2010-07-25)In the present study, a novel schiff bases were synthesized by condensation of 3-amino-2-methyl quinazolin-4-(3H)-ones with different aromatic aldehyde. The 3-amino-2-methyl quinazolin-4-(3H)-one was synthesized from ... -
Formulation and evaluation of chewable tablet of levamisole
(JK Welfare & Pharmascope Foundation, 2010-07-25)Levamisole is a synthetic imidazothiazole derivative that has been widely used in treatment of worm infestations in both humans and animals. As an anthelmintic, it probably works by targeting the nematode nicotinergic ... -
Chromatographic finger print analysis of budmunchiamines in Albizia amara by HPTLC technique
(JK Welfare & Pharmascope Foundation, 2010-07-25)Recently, there has been an increase in the use of herbal drugs for healthcare. Herbal Medicine is a time-tested and valuable resource for healing. In India, the herbal drug market is about $ one billion and the export of ... -
Formulation and evaluation of mouth dissolving tablets of losartan potassium by direct compression techniques
(JK Welfare & Pharmascope Foundation, 2010-07-25)In the present work, mouth dissolving tablets of losartan potassium were design with a view to enhance the patient compliance and provide a quick onset of action. Losartan potassium is an angiotensin receptor antagonist, ... -
Formulation and evaluation of once daily mucoahdesive vaginal tablet of metronidazole
(JK Welfare & Pharmascope Foundation, 2010-07-25)The antitrichomonal imidazole derivative metronidazole is employed locally for the treatment of genitourinary tract bacterial infections and is formulated as creams, foams, tablets, or irrigations. In this study, a new ... -
Evaluation of crude saponins extract from leaves of Sesbania sesban (L.) Merr. for topical anti-inflammatory activity
(JK Welfare & Pharmascope Foundation, 2010-07-25)Sesbania sesban is a short-lived shrub up to 8 m tall, which belongs to the family Leguminosae. Leaves are found to be rich in saponin content. The leaves of Sesbania sesban has traditionally been used as purgative, ... -
Simultaneous determination of gatifloxacin and ambroxol hydrochloride from tablet dosage form using RP-HPLC
(JK Welfare & Pharmascope Foundation, 2010-07-25)A reversed-phase high performance liquid chromatography (HPLC) method was developed, validated, and used for the quantitative determination of gatifloxacin (GA) and ambroxol hydrochloride (AM), from its tablet dosage form. ... -
Spectrophotometric determination of Tolperisone using 2, 4-dinitrophenylhydrazine reagent
(JK Welfare & Pharmascope Foundation, 2010-07-25)A simple, novel, sensitive, and specific spectrophotometric method was developed and validated for the determination of Tolperisone in bulk and its dosage forms. The proposed method was based on the interaction of the drug ... -
Development of Analytical Method for Lumefantrine by UV Spectrophotometry
(JK Welfare & Pharmascope Foundation, 2010-07-25)A Simple, sensitive, specific, spectrophotometric method has been developed for the detection of Lumefantrine in pure form and Pharmaceutical formulations. The optimum condition for the analysis of the drug was established. ... -
Formulation and Evaluation of Iontophoretic Transdermal Delivery of Dilti-azem Hydrochloride
(JK Welfare & Pharmascope Foundation, 2010-07-25)The purpose of this research work was to develop and evaluate Iontophoretic Transdermal Delivery of Diltiazem Hydrochloride with various hydrophilic polymers HPMC, SCMC and PVA with propylene glycol as plasticizer by solvent ... -
Investigation of effect of drug solubility on colon specificity of polysaccharide polymers khaya gum and guar gum
(JK Welfare & Pharmascope Foundation, 2010-07-25)The fast disintegrating core tablets of budesonide and domperidone, were prepared separately by direct compression technique. Later, these tablets were compression coated with khaya gum/guar gum, polysaccharide polymers. ...