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Absorption enhancement effect of piperine and chitosan on ganciclovir sol-id lipid nanoparticles: formulation, optimization and invivo pharmacokinetics
(JK Welfare & Pharmascope Foundation, 2019-04-14)The purpose of the present study was to formulate Solid Lipid Nanoparticles (SLNs) of Ganciclovir (GCV) in combination with Chitosan and Piperine for absorption enhancement effect. GCV loaded SLNs were prepared by hot ... -
Accelerated stability studies of niacin and green tea extract sustained release bilayer tablets with different polymers
(JK Welfare & Pharmascope Foundation, 2016-01-20)Niacin and Green tea extract are used for maintaining the lipid profile in Hyperlipidemia. Currently Statins are extensively used in the treatment of Hyperlipidemia which is known to cause rhabdomyolysis. The combination ... -
Accelerated stability study and quantitative estimation of piperine in Draksharishta
(JK Welfare & Pharmascope Foundation, 2017-04-14)The objective of the present study was to evaluate the accelerated stability study and estimation of piperine from Draksharishta. Accelerated stability study was done for 6 months to distinguish the stability of polyherbal ... -
Acetaminophen induced nephrotoxicity in experimental albino rats - Histopathological study
(JK Welfare & Pharmascope Foundation, 2018-07-12)Acetaminophen in overdose cause Nephrotoxicity (Acute Renal Failure) which exert toxic effects by one or more common mechanisms such as interglomerular hemodynamic tubular cell toxicity, inflammation, or decreased cellularity ... -
Acetylcholine esterase inhibition activity of gloriosa superba and molecular docking study of its constituents against bacterial proteins
(JK Welfare & Pharmascope Foundation, 2017-10-20)Plant materials are invaluable sources in treatment of various diseases and research on certain plants has opened the way to development of various therapeutic agents. In the present study, the chloroform extract from the ... -
Acetylcholinesterase inhibitory effect of capsicum oleoresins – an in vitro study
(JK Welfare & Pharmascope Foundation, 2018-10-12)The present study aimed to evaluate the acetylcholine esterase inhibitory effect of capsicum oleoresin. Capsicum extract were examined for their AChE inhibitory activities at different concentrations (10, 20, 40, 60, 80, ... -
Aconite: A pharmacological update
(JK Welfare & Pharmascope Foundation, 2012-04-25)Aconitine (Queen of Poisons) and related alkaloids found in the Aconitum species are highly toxic cardiotoxins and neurotoxins. Aconite is a herbaceous perennial plant, chiefly native of the northern hemisphere, growing ... -
Acoustical and thermal conductivity study of Ag nanofluids
(JK Welfare & Pharmascope Foundation, 2017-10-20)Nanofluid is a kind of navel engineering material consisting of metal particles with a size typically of 10nm–100 nm suspended in base fluid. These fluids offer the excellent scope of enhancing the thermal conductivity of ... -
Acute and chronic toxicity studies on Polygonum glabrum in experimental animals
(ScienzTech Publication, 2018-07-06)Polygonum glabrum is being used in traditional and folklore medicine to treat pneumonia and jaundice. Plant roots are used in ayurvedic preparations to treat fever and colic. The leaves are used as diuretic agents and ... -
Acute oral toxicity studies of isolated compounds in Lawsonia inermis and Leptadenia reticulata in swiss albino mice
(JK Welfare & Pharmascope Foundation, 2016-07-20)The compounds which is isolated from Leptadenia reticulata and Lawsonia inermis is sample 1 (6-amino-3-hydroxy-4-(4'-methylphenyl)-2Hchromen-2-on) and -sample 2 (3, 7, 4’, 5'-Tetrahydroxy-6- methoxyflavone). These compounds ... -
Acute toxicity on the ethanolic fruit extracts of Morinda sp. in Wistar albino rats
(JK Welfare & Pharmascope Foundation, 2015-01-25)The different maturity stages of ethanolic fruit extracts of Morinda citrifolia and Morinda tinctoria were evaluated for its acute toxicity effect on Wistar albino rats. The extracts were administered orally at the doses ... -
The added effect of cabergoline to metformin on serum hormones and rate and regularity of menstruation in women with Polycystic ovary syndrome
(JK Welfare & Pharmascope Foundation, 2018-01-10)Polycystic ovary syndrome (PCOS) is an important cause of menstrual irregularities and infertility in women. Management approaches are variable and share in common the objectives of improving menstrual irregularities, ... -
Adenosine deaminase as a screening test for the diagnosis of tuberculous pleural effusion
(JK Welfare & Pharmascope Foundation, 2013-07-15)Tuberculosis is one of the commonest infectious diseases, which affects lungs. In tubercular diseases, diagnosis of pulmonary tuberculosis is usually done by sputum examination for AFB. Pleural fluid biochemistry, cytology ... -
Alleviation of renal oxidative stress by Cassia alata in acetaminophen induced nephrotoxic rats
(JK Welfare & Pharmascope Foundation, 2018-10-25)This study was conducted to assess the protective and treatment effects of Cassia alata aqueous extract against acetaminophen-induced nephrotoxicity. 25 Sprague-Dawley rats were equally divided into 5 groups; (1) Healthy ... -
Altered metabolism of diabetes mellitus and its metabolic blockers
(JK Welfare & Pharmascope Foundation, 2012-07-25)The treatment of diabetes will not be perfect when it controls merely hyperglycemia. Hence, there are many multi dimensional approaches accelerated in diabetes research. In recent years, considerable progress has been made ... -
Ameliorative effect of Cleome gynandra Linn against scopolamine induced amnesia in mice
(JK Welfare & Pharmascope Foundation, 2017-10-20)The objective of this study was to evaluate various extracts of leaves of Cleome gynandra L for its memory enhancing ability. The exteroceptive behavioral models such as elevated plus maze, Morris water maze, Radial arm ... -
Analysis of Hydroethanolic leaf extract of Aerva lanata (L.) in screening antioxidant activity and in vitro antibacterial efficacy
(JK Welfare & Pharmascope Foundation, 2018-07-12)The present investigation has been carried out to evaluate antioxidant and antibacterial activity of ethanolic leaf extract of Aerva lanata L. The extracts were screened for their in vitro antioxidant potential Inhibition ... -
Analysis of macro and micro nutrients content in the leaves of Murraya koenigii (l.) sprenge
(JK Welfare & Pharmascope Foundation, 2018-01-10)The macro and micro nutrients content analysis was carried out for leaves of indigenous medicinal plant-Murraya Koenigii (L.) Sprenge collected from different places of North Karnataka region. The leaves of Murraya koenigii ... -
Analysis of papaya plant sample for antispermatogenic properties
(ScienzTech Publication, 2020-12-11)To advance new proof about the counter ripeness action of seeds concentrate of papaya (Carica papaya L.) in test creatures, particularly mice. Male mice (n=20) were assembled into four. The principal bunch got just purified ... -
Analysis of Strychnine and Brucine in hydro ethanolic extract of Strychnos Nux-Vomica leaves by using HPTLC
(JK Welfare & Pharmascope Foundation, 2017-01-10)Strychnos Nux-Vomica is a remedial plant used in herbal medicine and medicinal plants is having a curative history and are still helping healthiness requirements of a large population in the world. Therapeutic plants are ...