Browsing by Subject "HPMC"
Now showing items 1-11 of 11
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Design and evaluation of three layer matrix tablet of Losartan potassium capped with Eudragit and HPMC combination
(JK Welfare & Pharmascope Foundation, 2012-04-25)In the present investigation concern the formulation and evaluation of trilayer matrix tablets of losartan potassium (LP). Losartan potassium is an angiotensin-II receptor antagonist drug used mainly to treat high blood ... -
Development and evaluation of herbal gel formulation of Magnifera indica linn extract
(JK Welfare & Pharmascope Foundation, 2013-04-25)The aim of the present study is to develop topical gel formulation containing ethanol:water (80:20) dry extract of Mangifera indica L. and to evaluate its properties with respect to its quality, effectiveness against ... -
Development and evaluation of transdermal drug delivery system of metopro-lol
(JK Welfare & Pharmascope Foundation, 2012-10-25)Metoprolol (MP) is a potent ill-selective adrenergic blocking agent with proven antihypertensive activity. However, it undergoes extensive hepatic first-pass metabolism and has a short biological half-life, which necessitates ... -
Development, characterization of Glipizide spherical agglomerates by direct compression method
(JK Welfare & Pharmascope Foundation, 2017-10-20)The objective of the research is to prepare glipizide spherical agglomerates with increased solubility, flow and compression properties by novel crystallization technique. Glipizide was dissolved in 30ml dichloromethane ... -
Enhancement of solubility and dissolution rate of poorly water-soluble Etravirine by solid dispersion technique for antiretroviral therapy
(JK Welfare & Pharmascope Foundation, 2019-01-05)Solid dispersions (SDs) technique represents a promising approach to enhance the solubility, dissolution rate and bioavailability of poorly water-soluble drugs. Etravirine is a new non-nucleoside reverse transcriptase ... -
Fabrication and characterization of a matrix-type transdermal patch containing microspheres of risperidone
(JK Welfare & Pharmascope Foundation, 2019-01-05)One of the important problems in the case of psychotic patients is that of compliance with the therapy. Since the routes of administration are invasive, patients resist adhering to the treatment which reduces the efficacy. ... -
Formulation and Evaluation of a pH Induced In Situ Occular Gelling System of Ketorolac
(Pharma Springs Publication, 2022-05-30)A traditional fluid ophthalmologic delivery mechanisms illustrate concise pre-corneal retention time as well as the relates impermeability toward the cornea which results in low class ocular bioactivity. An objective of a ... -
Formulation and evaluation of extended-release tablets of an antidepres-sant drug Venlafaxine HCl
(JK Welfare & Pharmascope Foundation, 2018-10-12)Oral drug delivery is the most desirable and preferred method of administering therapeutic agents for their systemic effects. A dosage form that allows at least a twofold reduction in dosage frequency as compared to that ... -
In vitro antibacterial activities study of norfloxacin containing mucoadhesive suspensions
(JK Welfare & Pharmascope Foundation, 2012-04-25)To study the in vitro antibacterial properties of mucoadhesive suspensions containing Norfloxacin, three different formulations were prepared by using three polymers, such as Hydroxypropyl methylcellulose (HPMC) (S₁), ... -
Influence of polymeric precipitation inhibitors on dissolution behaviour of Meloxicam
(JK Welfare & Pharmascope Foundation, 2018-10-12)The scope of this study was to analyse the effect of polymeric precipitation inhibitor on in-vitro dissolution of Meloxicam which is a weak acid, water-insoluble and a crystalline compound. Meloxicam is used to treat pain ... -
Preparation and evaluation of buccal patches of losartan potassium using hydrophilic polymers
(JK Welfare & Pharmascope Foundation, 2013-04-25)Losartan potassium is an Angiotensin II receptor antagonist with a half life of 1.5-2 hrs and an oral bioavailability of only 33% due to extensive first pass metabolism. Mucoadhesive buccal films of losartan potassium were ...